Description

Rac trans-3-Amino-1-Oxyl-2,2,5,5-Tetramethylpyrrolidine-4-Carboxylic Acid CAS NO 15871-58-6 is a stable nitroxide radical derivative of the amino acid proline, serving as a versatile and persistent spin label and spin trap. Its core value lies in enabling advanced electron paramagnetic resonance (EPR) spectroscopy studies for probing molecular structure, dynamics, and interactions in complex systems. This compound is essential for researchers and developers in biophysics, structural biology, polymer science, and materials chemistry who require reliable tools for site-directed spin labeling and free radical analysis.

Application

• Site-Directed Spin Labeling (SDSL): Covalently attached to proteins, peptides, or nucleic acids to study conformational changes, folding, and macromolecular interactions via EPR spectroscopy.
• Polymer & Materials Science: Incorporated as a stable radical probe to investigate polymer chain dynamics, morphology, cross-linking density, and degradation mechanisms.
• Spin Trapping Agent: Used to detect, identify, and quantify short-lived free radicals in chemical, biological, and environmental systems.
• Oxidative Stress Research: Employed as a sensor or probe in models studying redox biology and antioxidant activity.
• MRI Contrast Agent Development: Serves as a building block for synthesizing novel contrast agents based on nitroxide radicals.
• Catalysis & Mechanistic Studies: Utilized to monitor radical intermediates and elucidate reaction mechanisms in catalytic processes.

Basic Information

Item	Detail
Product Name	Rac trans-3-Amino-1-Oxyl-2,2,5,5-Tetramethylpyrrolidine-4-Carboxylic Acid
CAS No.	15871-58-6
Molecular Formula	C9H17N2O3
Molecular Weight	201.25 g/mol
Synonyms	3-Amino-2,2,5,5-tetramethyl-1-pyrrolidinyloxy-4-carboxylic Acid; 3-Aminoproxyl-4-carboxylic Acid; 3-Amino-PROXYL-4-carboxylic Acid; 3-Amino-2,2,5,5-tetramethylpyrrolidine-1-oxyl-4-carboxylic Acid; 3-Amino-TEMPO-4-carboxylic Acid; 4-Carboxy-3-amino-2,2,5,5-tetramethylpyrrolidin-1-oxyl; 3-Amino-4-carboxy-PROXYL; rac-3-ATPC
EINECS	Contact for details

Quality Control

Our production of Rac trans-3-Amino-1-Oxyl-2,2,5,5-Tetramethylpyrrolidine-4-Carboxylic Acid adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high radical purity. Each lot is characterized using advanced analytical techniques, including HPLC, EPR, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment, supporting research reproducibility and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and prolong shelf-life. Keep the container in a cool, dry, and well-ventilated area separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (EPR)	Characteristic triplet signal
Purity (HPLC)	≥ 97.0%
Assay (EPR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.