Description

Deuterium Oxide-18O is a stable, isotopically labeled form of water, also known as doubly labeled water, containing both deuterium (²H) and the oxygen-18 (¹⁸O) isotope. This unique compound is an essential tracer and analytical standard in advanced scientific research, enabling precise metabolic and kinetic studies. It is critically needed by researchers and analytical laboratories in the fields of pharmaceutical development, environmental science, metabolic research, and nuclear magnetic resonance (NMR) spectroscopy.

Application

• Metabolic Research Tracer: Used in doubly labeled water (DLW) studies to measure total energy expenditure, CO₂ production, and metabolic rates in humans and animals.
• Pharmaceutical Development: Serves as a critical internal standard and tracer in pharmacokinetic studies, drug metabolism research, and the synthesis of isotopically labeled drug candidates.
• NMR Spectroscopy Solvent: Acts as an ideal solvent for NMR analysis, particularly for proton-sensitive experiments, due to its reduced interference in the ¹H NMR spectrum.
• Environmental & Hydrological Tracing: Employed as a tracer to study water movement, groundwater flow, and ecosystem processes.
• Chemical Reaction Mechanism Studies: Utilized to elucidate reaction pathways and kinetics in organic and inorganic chemistry by tracking the fate of oxygen atoms.
• Analytical Standard: Provides a certified reference material for calibrating mass spectrometers and other analytical instruments in isotope ratio analysis.

Basic Information

Product Name	Deuterium Oxide-18O
CAS No.	14674-67-0
Molecular Formula	²H₂¹⁸O
Molecular Weight	22.03 g/mol
Synonyms	Water-d2-18O; Doubly Labeled Water (DLW); Deuterium Oxide (18O); D₂¹⁸O; Heavy Water-18O; ¹⁸O-Labeled Heavy Water; [¹⁸O]Water-d2; Oxygen-18 Water-d2
EINECS	Contact for details

Quality Control

Our Deuterium Oxide-18O is produced and handled under stringent quality management protocols. Each batch is analyzed to confirm isotopic enrichment (for both ²H and ¹⁸O), chemical purity, and absence of key impurities. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, assay, and specific tests is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Due to its hygroscopic nature and the critical importance of maintaining isotopic purity, containers should be kept sealed when not in use to prevent atmospheric exchange and contamination.

Specification

Item	Specification
Appearance	Colorless Clear Liquid
Identification (IR)	Conforms
Isotopic Purity (¹⁸O)	≥ 95 atom %
Isotopic Purity (Deuterium, ²H)	≥ 99 atom %
Assay (D₂¹⁸O)	≥ 98.0%
Chemical Purity (by GC)	≥ 99.5%
Conductivity	≤ 5 µS/cm
pH	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.