Description

2,2,6,6-Tetramethylpiperidine-1-Oxyl-4-Amino-4-Carboxylic Acid is a stable nitroxide radical derivative of the TEMPO (2,2,6,6-tetramethylpiperidine 1-oxyl) family, distinguished by its bifunctional amino and carboxylic acid groups. This compound matters as a versatile building block and spin label, enabling advanced research and development in polymer chemistry, materials science, and biochemistry. It is essential for researchers and manufacturers in the pharmaceutical, specialty polymer, and advanced materials sectors who require a functionalized, stable radical for controlled polymerization, surface modification, or as a paramagnetic probe.

Application

• Polymer Science & Controlled Radical Polymerization (CRP): Acts as a functional initiator, mediator, or chain transfer agent in Nitroxide-Mediated Polymerization (NMP) for synthesizing well-defined polymers and block copolymers with precise architectures.
• Bioconjugation & Spin Labeling: The amino and carboxyl groups facilitate covalent attachment to biomolecules (proteins, peptides, nucleic acids) for Electron Paramagnetic Resonance (EPR) spectroscopy studies of structure and dynamics.
• Surface Modification & Functionalization: Used to graft stable nitroxide radicals onto nanoparticles, polymers, or solid supports to create active surfaces for further chemical reactions or as persistent radical surfaces.
• Antioxidant & Stabilizer Research: Serves as a model compound or precursor in developing novel antioxidants and stabilizers for plastics, fuels, and lubricants due to its radical scavenging properties.
• Organic Synthesis & Catalyst Design: Employed as a chiral auxiliary or ligand precursor in asymmetric synthesis and catalysis, leveraging its rigid piperidine structure.
• Materials for Molecular Electronics: Investigated as a component in the design of organic magnetic materials, molecular switches, and spintronic devices.

Basic Information

Product Name	2,2,6,6-Tetramethylpiperidine-1-Oxyl-4-Amino-4-Carboxylic Acid
CAS No.	15871-57-5
Molecular Formula	C10H19N2O3
Molecular Weight	215.27 g/mol
Synonyms	4-Amino-4-carboxy-TEMPO; 4-Amino-TEMPO-4-carboxylic acid; 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-4-carboxylic acid; 4-AT; 4-Amino-TEMPO acid; 4-Carboxy-4-amino-2,2,6,6-tetramethylpiperidin-1-oxyl; 4-Amino-4-carboxy-2,2,6,6-tetramethylpiperidine-1-oxyl; 1-Oxyl-4-amino-4-carboxy-2,2,6,6-tetramethylpiperidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research and industrial standards. Key parameters such as radical purity, enantiomeric purity (if applicable), and functional group integrity are verified. A comprehensive Certificate of Analysis (COA) detailing assay, identification, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. This compound is light-sensitive and easily oxidized. Keep away from strong oxidizing and reducing agents.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Radical Content (EPR)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.