Description

3-(tert-Butyl)-1H-Pyrazole is a versatile heterocyclic organic compound belonging to the pyrazole class, characterized by a tert-butyl substituent at the 3-position. This specific substitution pattern makes it a valuable and highly sought-after chemical building block and pharmaceutical intermediate for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Serves as a core scaffold for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand in Catalysis: Used to synthesize N-heterocyclic carbene (NHC) precursors and other specialized ligands for transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probe: Acts as a modular component for creating tool compounds and probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	3-(tert-Butyl)-1H-Pyrazole
CAS No.	15802-80-9
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	3-tert-Butyl-1H-pyrazole; 3-(1,1-Dimethylethyl)-1H-pyrazole; 1H-Pyrazole, 3-(1,1-dimethylethyl)-; 3-(tert-Butyl)pyrazole; 3-t-Butylpyrazole; 3-(tert-Butyl)pyrazole; tert-Butylpyrazole
EINECS	Contact for details

Quality Control

Our production of 3-(tert-Butyl)-1H-Pyrazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure high chemical consistency and reproducibility. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects requiring material produced under ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.