Description

Bis(4-Bromophenyl)Phosphine Oxide is a high-purity organophosphorus compound characterized by its brominated aromatic structure, serving as a versatile intermediate in advanced chemical synthesis. Its primary value lies in its role as a key precursor for the development of ligands, flame retardants, and functional materials, where its specific bromine substitution pattern is critical. This product is essential for R&D and production within the pharmaceutical, agrochemical, and specialty polymer industries, particularly for researchers and manufacturers requiring high-quality, reliable building blocks for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those targeting kinase inhibition.
• Ligand Synthesis: Serves as a precursor for the preparation of specialized phosphine ligands used in transition metal catalysis, such as cross-coupling reactions.
• Flame Retardant Synthon: Used in the development and production of brominated flame retardants for engineering plastics and epoxy resins.
• Material Science Research: Employed in the creation of organic light-emitting diodes (OLEDs), photoresists, and other advanced electronic materials.
• Agrochemical Synthesis: Acts as an intermediate in the manufacture of certain herbicides, fungicides, and plant growth regulators.
• Cross-Coupling Reactions: Utilized in Suzuki, Heck, and other palladium-catalyzed coupling reactions to create complex biaryl structures.

Basic Information

Product Name	Bis(4-Bromophenyl)Phosphine Oxide
CAS No.	15754-53-7
Molecular Formula	C12H8Br2OP
Molecular Weight	359.97 g/mol
Synonyms	Bis(p-Bromophenyl)Phosphine Oxide; (4-Bromophenyl)phosphonic Acid Bis(4-bromophenyl) Ester; Phosphine Oxide, Bis(4-bromophenyl)-; 4,4'-Dibromodiphenylphosphine Oxide; p-Bromophenylphosphine Oxide Dimer; 1,1'-(Oxidophosphinidene)bis(4-bromobenzene); NSC 163081
EINECS	Contact for details

Quality Control

Our Bis(4-Bromophenyl)Phosphine Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.