Description

5-Bromo-4,6-dihydroxypyrimidine is a halogenated pyrimidine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure makes it a valuable precursor for the development of complex heterocyclic compounds, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), nucleoside analogs, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel antiviral, anticancer, and antibacterial agents, particularly in nucleoside chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require halogenated pyrimidine cores.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex fused heterocyclic systems.
• Material Science Precursor: Investigated for the synthesis of organic ligands and functional molecules used in coordination chemistry and advanced materials.
• Biochemical Research: Utilized in the study of enzyme inhibitors and the preparation of modified nucleobases for probing biological mechanisms.

Basic Information

Product Name	5-Bromo-4,6-dihydroxypyrimidine
CAS No.	15726-38-2
Molecular Formula	C4H3BrN2O2
Molecular Weight	190.98 g/mol
Synonyms	5-Bromo-4,6-pyrimidinediol; 4,6-Dihydroxy-5-bromopyrimidine; 5-Bromopyrimidine-4,6-diol; 5-Bromo-4,6-dihydroxy-1,3-diazine; 5-Bromobarbituric Acid (common misnomer); 5-Bromouracil precursor; NSC 403697
EINECS	Contact for details

Quality Control

Our 5-Bromo-4,6-dihydroxypyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with ICH guidelines for impurities and can provide material suitable for research and development under current Good Manufacturing Practice (cGMP) standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.