Description

2-(3-Methoxybenzylidene)-3-Oxobutyric Acid Ethyl Ester is a versatile organic intermediate characterized by its conjugated keto-ester structure. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocyclic frameworks and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those containing benzylidene or chalcone motifs with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive α,β-unsaturated carbonyl system.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and functional materials requiring specific conjugated molecular architectures.
• Academic & Industrial Research: Employed in organic synthesis methodologies, including studies on Michael additions, cyclization reactions, and catalysis.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, method development, and quality control in chemical manufacturing.

Basic Information

Product Name	2-(3-Methoxybenzylidene)-3-Oxobutyric Acid Ethyl Ester
CAS No.	15725-25-4
Molecular Formula	C₁₄H₁₆O₄
Molecular Weight	248.28 g/mol
Synonyms	Ethyl 2-(3-Methoxybenzylidene)-3-oxobutanoate; Ethyl (3-Methoxybenzylidene)acetoacetate; 3-Oxobutyric Acid, 2-(3-Methoxybenzylidene)-, Ethyl Ester; 2-(3-Methoxybenzylidene)acetoacetic Acid Ethyl Ester; 3-Methoxybenzylideneacetoacetic Acid Ethyl Ester; Ethyl 3-(3-Methoxyphenyl)-2-methylenebut-3-enoate (tautomeric form); Ethyl (Z/E)-2-(3-Methoxybenzylidene)-3-oxobutanoate
EINECS	Contact for details

Quality Control

Our 2-(3-Methoxybenzylidene)-3-Oxobutyric Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.