Description

4α-tert-Butylcyclohexane-1α-Carbonitrile is a specialized organic nitrile compound characterized by its unique sterically hindered cyclohexane structure. This molecular architecture makes it a valuable chiral intermediate and building block in advanced organic synthesis, particularly for the development of complex, high-value molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications requiring precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the tert-butylcyclohexyl moiety contributes to biological activity and stability.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Building Block: Employed in the synthesis of fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemical configurations.
• Material Science Research: Investigated as a monomer or additive for creating polymers with tailored thermal and mechanical properties.

Basic Information

Product Name	4α-tert-Butylcyclohexane-1α-Carbonitrile
CAS No.	15619-19-9
Molecular Formula	C11H19N
Molecular Weight	165.28 g/mol
Synonyms	trans-4-tert-Butylcyclohexanecarbonitrile; 4-tert-Butylcyclohexanecarbonitrile; 4-(1,1-Dimethylethyl)cyclohexanecarbonitrile; 4-tert-Butyl-1-cyanocyclohexane; 4-tert-Butylcyclohexyl cyanide; p-tert-Butylcyclohexanecarbonitrile; 4-tert-Butylcyclohexanenitrile
EINECS	Contact for details

Quality Control

Our 4α-tert-Butylcyclohexane-1α-Carbonitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric excess (where applicable), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Typical 98.5%)
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.