Description

(3S)-3-Methyl-1,2,3,4-Tetrahydroisoquinoline CAS NO 15547-43-0 is a chiral, non-racemic tetrahydroisoquinoline derivative, a versatile building block in organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for imparting specific biological activity or material properties in advanced applications. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of bioactive molecules, including potential central nervous system (CNS) agents, alkaloids, and enzyme inhibitors.
• Asymmetric Catalysis: Used as a precursor for chiral ligands or organocatalysts in enantioselective synthesis, critical for producing single-isomer compounds.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex natural products, dyes, and specialty chemicals where the tetrahydroisoquinoline scaffold is required.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and organic electronic materials.

Basic Information

Product Name	(3S)-3-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	15547-43-0
Molecular Formula	C10H13N
Molecular Weight	147.22 g/mol
Synonyms	(S)-3-Methyl-1,2,3,4-tetrahydroisoquinoline; (S)-3-Methyl-3,4-dihydro-1H-isoquinoline; (3S)-3-Methyl-3,4-dihydroisoquinoline; L-3-Methyl-1,2,3,4-tetrahydroisoquinoline; (-)-3-Methyl-1,2,3,4-tetrahydroisoquinoline; (S)-3-Methyl-THIQ; 1,2,3,4-Tetrahydro-3(S)-methylisoquinoline
EINECS	Contact for details

Quality Control

Our (3S)-3-Methyl-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC, GC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.