Description

1,3-Dimethyl-2-Phospholene 1-Oxide is a versatile organophosphorus compound, specifically a cyclic phosphine oxide, valued for its unique reactivity as a strong base and its solubility in organic media. This compound is a critical reagent and intermediate in advanced organic synthesis, particularly in the formation of carbon-phosphorus bonds and as a catalyst component. It is essential for R&D chemists and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those containing phosphorus heterocycles.
• Catalyst & Ligand Precursor: Used in the preparation of specialized catalysts and ligands for transition metal-catalyzed reactions, including cross-couplings.
• Agrochemical Synthesis: Employed in the research and production of advanced pesticides and herbicides where phosphorus-based chemistry is required.
• Material Science: Acts as a monomer or additive in the development of flame-retardant polymers and other functional materials.
• Organic Synthesis Reagent: Functions as a strong, non-nucleophilic base and a phosphorylating agent in various condensation and cyclization reactions.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new reaction methodologies and organophosphorus chemistry.

Basic Information

Product Name	1,3-Dimethyl-2-Phospholene 1-Oxide
CAS No.	15450-68-7
Molecular Formula	C6H11OP
Molecular Weight	130.13 g/mol
Synonyms	1,3-Dimethyl-2-phospholene 1-oxide; 1,3-Dimethylphospholene oxide; 2,5-Dihydro-1,3-dimethyl-1H-phosphole 1-oxide; DMPO; 1,3-Dimethyl-1-phosphacyclopent-2-ene 1-oxide; 1,3-Dimethyl-δ²-phospholene 1-oxide; 1,3-Dimethylphosphol-2-ene 1-oxide
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-2-Phospholene 1-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.