Description

n-Methylsaccharin is a versatile synthetic organic compound primarily used as a key intermediate in pharmaceutical and fine chemical synthesis. Its value lies in its role as a precursor for developing new chemical entities, particularly in medicinal chemistry where the saccharin scaffold is modified for biological activity. This product is essential for research and development laboratories, pharmaceutical manufacturers, and companies specializing in advanced organic synthesis seeking to create novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of new drug candidates, particularly those targeting enzymes or receptors where the methylated saccharin moiety is pharmacologically active.
• Agrochemical Research: Used in developing novel herbicides, pesticides, and plant growth regulators that incorporate heterocyclic structures for enhanced efficacy.
• Fine Chemical Synthesis: Serves as a specialized reagent for constructing complex molecules in academic and industrial research settings.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing high-value aromatic compounds, though not used as a sweetener itself.
• Material Science: Investigated as a monomer or additive in the development of specialized polymers with unique properties.
• Chemical Biology Probes: Utilized in creating molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	n-Methylsaccharin
CAS No.	15448-99-4
Molecular Formula	C8H7NO3S
Molecular Weight	197.21 g/mol
Synonyms	1-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-Dioxide; 1-Methylsaccharin; N-Methylsaccharin; 3-Oxo-1-methyl-1,2-benzisothiazoline-1,1-dioxide; Methyl saccharin; 1,2-Benzisothiazol-3(2H)-one, 1-methyl-, 1,1-dioxide; 2,3-Dihydro-1-methyl-3-oxo-1,2-benzisothiazole-1,1-dioxide
EINECS	Contact for details

Quality Control

Our n-Methylsaccharin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. For customers with specific purity requirements, including pharmaceutical-grade specifications, we offer tailored quality control protocols and can accommodate custom analytical testing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	228 - 232 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.