Description

5-(1,1-Dimethylethyl)-5-Ethylbarbituric Acid is a specialized barbiturate derivative, a key intermediate in the synthesis of more complex pharmaceutical compounds. Its value lies in its precise chemical structure, which serves as a foundational building block for developing active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the development and production of central nervous system (CNS) agents and other therapeutic molecules.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of barbiturate-based active pharmaceutical ingredients (APIs).
• CNS Drug Research: Key starting material in medicinal chemistry for the research and development of new sedative, hypnotic, or anticonvulsant agents.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to create complex molecular architectures for specialized applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating the mechanism of action of barbiturates and related compounds at receptor sites.
• Chemical Library Development: A valuable compound for building diverse screening libraries in drug discovery programs.

Basic Information

Product Name	5-(1,1-Dimethylethyl)-5-Ethylbarbituric Acid
CAS No.	15379-32-5
Molecular Formula	C10H16N2O3
Molecular Weight	212.25 g/mol
Synonyms	5-tert-Butyl-5-ethylbarbituric Acid; 5-tert-Butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-(tert-Butyl)-5-ethylbarbituric Acid; 5-Ethyl-5-(1,1-dimethylethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-tert-butylbarbituric Acid; NSC 163047; 5-(tert-Butyl)-5-ethyl-1,3-diazinane-2,4,6-trione
EINECS	Contact for details

Quality Control

Our 5-(1,1-Dimethylethyl)-5-Ethylbarbituric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.