Description

3,4-Dehydro-β-Lapachone is a synthetic derivative of the naturally occurring quinone, β-lapachone, characterized by its distinctive dehydro structure. This compound is of significant interest in advanced research and development due to its potential as a biochemical tool and a precursor for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on oncology, anti-infective, and redox biology studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel anticancer and antimicrobial agents.
• Biochemical Tool Compound: Used in vitro and in vivo studies to investigate mechanisms related to NAD(P)H:quinone oxidoreductase 1 (NQO1) and reactive oxygen species (ROS) generation.
• Academic Research: Employed in university and institutional labs for fundamental research in medicinal chemistry, chemical biology, and pharmacology.
• Preclinical Studies: Acts as a candidate molecule for evaluating efficacy, pharmacokinetics, and toxicology in disease models.
• Specialty Chemical Synthesis: Used as a building block for creating more complex quinone-based compounds with tailored biological activities.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in related compound manufacturing.

Basic Information

Product Name	3,4-Dehydro-β-Lapachone
CAS No.	15297-93-5
Molecular Formula	C₁₅H₁₂O₃
Molecular Weight	240.26 g/mol
Synonyms	3,4-Dehydro-β-lapachone; 2,2-Dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione; Dehydro-β-lapachone; NSC 263836; β-Lapachone Dehydro Derivative; 2,2-Dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione
EINECS	Contact for details

Quality Control

Our 3,4-Dehydro-β-Lapachone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications. Our quality commitment supports applications requiring high-purity, well-characterized chemical entities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.