Description

Ginkgolide B is a highly purified, biologically active terpene lactone isolated from *Ginkgo biloba* leaves. This specific compound is valued for its potent and selective antagonism of the platelet-activating factor (PAF) receptor, making it a critical reference standard and a key ingredient for advanced research and development. It is essential for pharmaceutical companies, nutraceutical manufacturers, and research institutions focused on neuroprotection, cardiovascular health, and inflammation. Our supply of Ginkgolide B CAS NO 15291-77-7 ensures high purity and batch-to-batch consistency for reliable experimental and commercial outcomes.

Application

• Pharmaceutical Reference Standard: Used as a primary chemical reference material (CRM) for the quality control and standardization of Ginkgo biloba extracts and finished pharmaceutical products.
• Neuroprotective Research: A vital tool in preclinical studies investigating mechanisms for Alzheimer's disease, stroke, and other neurodegenerative conditions due to its effects on cerebral circulation and neuronal protection.
• Cardiovascular & Anti-inflammatory Studies: Employed in research targeting atherosclerosis, asthma, and other inflammatory disorders through its specific PAF receptor inhibition.
• Nutraceutical & Dietary Supplement Formulation: Incorporated into high-grade supplements where standardized, active constituent content is required for efficacy claims and product differentiation.
• Analytical Chemistry: Serves as a critical calibration standard in HPLC, LC-MS, and other analytical methods for quantifying ginkgolide content in complex matrices.
• Cosmeceutical Development: Explored in premium skincare formulations for its potential antioxidant and microcirculation-enhancing properties.

Basic Information

Product Name	Ginkgolide B
CAS No.	15291-77-7
Molecular Formula	C20H24O11
Molecular Weight	440.40 g/mol
Synonyms	BN 52021; Ginkgolide B; (1R,2S,3R,6R,10S,14S)-5,10-Dihydroxy-3,14-dihydroxy-4,8,13,17-tetramethyl-11,16-dioxatetracyclo[12.2.1.13,6.18,11]heptadecane-4,9,15-trione; (3aS,3bR,4S,5aS,6R,7aS,8R,10aS,10bS)-Decahydro-4,6-dihydroxy-3b,5a,8-trimethyl-3H-3a,6-epoxy-2-benzoxepin-7(1H)-one; PAF Receptor Antagonist BN 52021
EINECS	Contact for details

Quality Control

Our Ginkgolide B is produced and tested under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and heavy metals is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant use and storage under inert atmosphere to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.