Description

3,4-Methylenedioxy-α-Phenyl-4'-[2-(1-Pyrrolidinyl)Ethoxy]Chalcone CAS NO 15272-65-8 is a specialized synthetic chalcone derivative, a class of compounds known for their diverse biological activities. This high-purity intermediate is critical for research and development in advanced pharmaceutical and agrochemical synthesis. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for its role as a key building block in creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies to develop and optimize new chemical entities with enhanced biological potency and selectivity.
• Biochemical Tool Compound: Employed in pharmacological assays and as a reference standard to study specific biological pathways and receptor interactions.
• Agrochemical Development: Acts as an intermediate in the research and synthesis of new-generation pesticides and herbicides with novel modes of action.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in organic chemistry and drug discovery projects.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client pipelines.

Basic Information

Product Name	3,4-Methylenedioxy-α-Phenyl-4'-[2-(1-Pyrrolidinyl)Ethoxy]Chalcone
CAS No.	15272-65-8
Molecular Formula	C28H27NO4
Molecular Weight	441.52 g/mol
Synonyms	4'-[2-(1-Pyrrolidinyl)ethoxy]-3,4-methylenedioxychalcone; 1-[4-[2-(Pyrrolidin-1-yl)ethoxy]phenyl]-3-(1,3-benzodioxol-5-yl)prop-2-en-1-one; 3,4-(Methylenedioxy)-α-phenyl-4'-[2-(1-pyrrolidinyl)ethoxy]chalcone; NSC 351135; Chalcone derivative, Pyrrolidinylethoxychalcone; MDL 101,002 (Research Code); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 3,4-Methylenedioxy-α-Phenyl-4'-[2-(1-Pyrrolidinyl)Ethoxy]Chalcone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications tailored to meet project-specific requirements. A detailed Certificate of Analysis (COA) documenting purity (typically by HPLC), identity (by IR, NMR), and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0% (Research Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.