Description

(-)-3-Chloro-n-(α-Methylphenethyl)-Propionamide is a chiral organic compound featuring a chloro-substituted propionamide moiety linked to an α-methylphenethyl group. This specific stereochemistry and functional group arrangement make it a valuable chiral intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for the synthesis of enantiomerically pure compounds, including potential active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecules with defined three-dimensional structures.
• Ligand and Catalyst Development: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals, agrochemicals, and advanced materials.
• Academic and Industrial Research: Used in methodological studies and process chemistry development for new synthetic routes.

Basic Information

Product Name	(-)-3-Chloro-n-(α-Methylphenethyl)-Propionamide
CAS No.	15269-41-7
Molecular Formula	C₁₂H₁₆ClNO
Molecular Weight	225.72 g/mol
Synonyms	(-)-3-Chloro-N-(1-phenylpropan-2-yl)propanamide; (S)-3-Chloro-N-(1-phenylpropan-2-yl)propanamide; (S)-3-Chloro-N-(α-methylphenethyl)propionamide; L-3-Chloro-N-(α-methylphenethyl)propionamide; 15269-41-7; (-)-3-Chloro-N-(α-methylphenethyl)propionamide; Propionamide, 3-chloro-N-[(1S)-1-methyl-2-phenylethyl]-
EINECS	Contact for details

Quality Control

Our (-)-3-Chloro-n-(α-Methylphenethyl)-Propionamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC, Chiral GC), identity confirmation (IR, NMR), and determination of chemical purity and related substances. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.