Description

5-Hexyn-1-Amine is a bifunctional organic compound featuring both a terminal alkyne and a primary amine group, making it a versatile building block in synthetic chemistry. This unique structure is critical for applications requiring selective cross-coupling or click chemistry reactions, enabling the construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediates: Serves as a key synthon in the synthesis of potential drug candidates, particularly through Sonogashira coupling or as a component in Huisgen cycloaddition (click chemistry) to create triazole linkages.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require alkyne-amine functionalization.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, dendrimers, and surface-modified materials with tailored properties.
• Bioconjugation: Utilized in proteomics and diagnostics for labeling biomolecules (proteins, antibodies) via its reactive amine and alkyne groups.
• Ligand & Catalyst Development: Employed in the preparation of novel nitrogen-containing ligands for metal catalysis and organocatalysts.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-Hexyn-1-Amine
CAS No.	15252-45-6
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	5-Hexyn-1-amine; 6-Amino-1-hexyne; 1-Amino-5-hexyne; 5-Hexynylamine; Hex-5-yn-1-amine; 5-Hexyne-1-amine; Amino-5-hexyne; 15252-45-6
EINECS	Contact for details

Quality Control

Our 5-Hexyn-1-Amine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its properties of being easily oxidized and highly volatile, it is recommended to store at 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.