Description

2-Hydroxymethyl-Cyclopropanecarboxylic Acid Ethyl Ester is a versatile cyclopropane derivative that serves as a key chiral building block in advanced organic synthesis. Its unique structure, featuring both ester and hydroxymethyl functional groups on a strained three-membered ring, makes it valuable for constructing complex molecular architectures with precise stereochemistry. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific three-dimensional structures.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with unique thermal and mechanical properties.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry, particularly in ring-opening and functionalization reactions of strained systems.

Basic Information

Product Name	2-Hydroxymethyl-Cyclopropanecarboxylic Acid Ethyl Ester
CAS No.	15224-11-0
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Ethyl 2-(Hydroxymethyl)cyclopropanecarboxylate; Ethyl 2-(Hydroxymethyl)cyclopropane-1-carboxylate; 2-(Hydroxymethyl)cyclopropanecarboxylic Acid Ethyl Ester; Cyclopropanecarboxylic acid, 2-(hydroxymethyl)-, ethyl ester; 1-Cyclopropanecarboxylic acid, 2-(hydroxymethyl)-, ethyl ester; Ethyl 2-Hydroxymethylcyclopropanecarboxylate; (Hydroxymethyl)cyclopropanecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Hydroxymethyl-Cyclopropanecarboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be hygroscopic; protect from excessive moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.