Description

(1S,2β,7Aα)-1,2-Epoxyhexahydro-1H-Pyrrolizine-1-Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolizine-based epoxide structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile chiral building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of specialized therapeutics and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex nitrogen-containing heterocycles.
• Medicinal Chemistry Research: Used as a versatile building block for constructing molecular libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialized fine chemicals, agrochemicals, and other high-value compounds requiring its specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for universities and corporate R&D laboratories focused on organic synthesis methodology and the development of novel synthetic routes.

Basic Information

Product Name	(1S,2β,7Aα)-1,2-Epoxyhexahydro-1H-Pyrrolizine-1-Methanol
CAS No.	15211-03-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol; 1H-Pyrrolizine-1-methanol, 1,2-epoxyhexahydro-; (1S,2R,7aR)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol; Pyrrolizine epoxide methanol derivative; 1-(Hydroxymethyl)-1,2-epoxyhexahydropyrrolizine; Chiral pyrrolizine epoxide intermediate
EINECS	Contact for details

Quality Control

Our (1S,2β,7Aα)-1,2-Epoxyhexahydro-1H-Pyrrolizine-1-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.