Description

4,4,4-Trifluoro-1-(2-Methoxy-Phenyl)-Butane-1,3-Dione is a specialized fluorinated diketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a methoxyphenyl moiety, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those requiring fluorinated scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for creating advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental profile.
• Ligand and Catalyst Development: Used in the preparation of specialized chelating ligands and organometallic catalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for electronic materials, liquid crystals, and polymers with specific optical or thermal properties.
• Chemical Research & Development: A versatile reagent for method development in organic chemistry, enabling the study of new fluorination and condensation reactions.

Basic Information

Product Name	4,4,4-Trifluoro-1-(2-Methoxy-Phenyl)-Butane-1,3-Dione
CAS No.	15191-69-2
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	1-(2-Methoxyphenyl)-4,4,4-trifluorobutane-1,3-dione; 4,4,4-Trifluoro-1-(2-methoxyphenyl)-1,3-butanedione; 2-Methoxyphenyl 4,4,4-trifluoroacetoacetate; 2'-Methoxy-4,4,4-trifluoroacetylacetophenone; TFMAA (common abbreviation); 15191-69-2; 4,4,4-Trifluoro-1-(o-methoxyphenyl)-1,3-butanedione
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-(2-Methoxy-Phenyl)-Butane-1,3-Dione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.