Description

2-Hydroxy-5-[(Trifluoromethyl)Sulphonyl]Nitrobenzene, 4-Hydroxy-3-Nitrophenyl Trifluoromethyl Sulphone is a specialized organic intermediate featuring a unique combination of nitro, hydroxyl, and trifluoromethylsulfonyl functional groups. This compound is valued for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular design. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those requiring sulfone or trifluoromethyl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the nitro and sulfone groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments due to its nitro-aromatic structure.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry exploration in academic and industrial laboratories.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other cross-coupling reactions to construct more complex biaryl systems.

Basic Information

Product Name	2-Hydroxy-5-[(Trifluoromethyl)Sulphonyl]Nitrobenzene, 4-Hydroxy-3-Nitrophenyl Trifluoromethyl Sulphone
CAS No.	15183-75-2
Molecular Formula	C7H4F3NO5S
Molecular Weight	271.17 g/mol
Synonyms	4-Hydroxy-3-nitrobenzenesulfonyl fluoride, trifluoromethylated; 2-Nitro-4-(trifluoromethylsulfonyl)phenol; 5-(Trifluoromethylsulfonyl)-2-nitrophenol; 3-Nitro-4-(trifluoromethylsulfonyl)phenol; 4-Hydroxy-3-nitrophenyl trifluoromethyl sulfone; 2-Hydroxy-5-(trifluoromethylsulfonyl)nitrobenzene; 15183-75-2; Phenol, 2-nitro-4-[(trifluoromethyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our production of 2-Hydroxy-5-[(Trifluoromethyl)Sulphonyl]Nitrobenzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity assay and identity confirmation via FT-IR and NMR spectroscopy. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.