Description

Cyclopropane, 1-Bromo-2-Ethenyl-, trans- (9Ci) is a specialized halogenated cyclopropane derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a bromine atom and a vinyl group on the cyclopropane ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring cyclopropane motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclopropane ring can confer specific biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in [3+2] cycloadditions, cross-coupling reactions (e.g., Suzuki, Heck), and other transition metal-catalyzed transformations to create complex, strained-ring systems.
• Ligand and Catalyst Development: Utilized to synthesize novel chiral ligands or organocatalysts that incorporate the sterically defined cyclopropane framework.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme mechanisms or protein-ligand interactions due to its potential as a reactive handle (bromine) and structural element.

Basic Information

Item	Detail
Product Name	Cyclopropane, 1-Bromo-2-Ethenyl-, trans- (9Ci)
CAS No.	15136-02-4
Molecular Formula	C5H7Br
Molecular Weight	147.01 g/mol
Synonyms	trans-1-Bromo-2-vinylcyclopropane; (1R,2S)-1-Bromo-2-vinylcyclopropane; (1S,2R)-1-Bromo-2-vinylcyclopropane; 1-Bromo-2-ethenylcyclopropane, trans-; 2-Vinylcyclopropyl bromide; Bromo(vinyl)cyclopropane; NSC 163044
EINECS	Contact for details

Quality Control

Our Cyclopropane, 1-Bromo-2-Ethenyl-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept sealed and handled under an inert atmosphere when possible to maintain purity and prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (trans-)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.