Description

4-(Chloromethyl)-1,3,2-Dioxathiolane 2-Oxide is a versatile and reactive cyclic sulfite ester, widely recognized by its CAS number 15121-11-6. This compound serves as a critical sulfonation and alkylation reagent in advanced organic synthesis, enabling the introduction of functional groups under controlled conditions. It is primarily sought by pharmaceutical intermediates manufacturers and fine chemical producers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for active pharmaceutical ingredients (APIs), particularly in sulfonate ester chemistry.
• Polymer Modification: Used as a functional monomer or cross-linking agent to introduce reactive sites into polymer chains.
• Agrochemical Production: Intermediate in the synthesis of herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Chemical Research & Development: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies.
• Surface Functionalization: Applied to modify material surfaces for improved adhesion or specific chemical properties.

Basic Information

Product Name	4-(Chloromethyl)-1,3,2-Dioxathiolane 2-Oxide
CAS No.	15121-11-6
Molecular Formula	C3H5ClO3S
Molecular Weight	156.59 g/mol
Synonyms	4-(Chloromethyl)-1,3,2-dioxathiolane 2-oxide; Chloromethyl ethylene sulfite; 2-Chloromethyl-1,3,2-dioxathiolane 2-oxide; Ethylene chloromethyl sulfite; (Chloromethyl)ethylene sulfite; 1,3,2-Dioxathiolane, 4-(chloromethyl)-, 2-oxide; Cyclic sulfite of chloromethyl ethylene glycol
EINECS	Contact for details

Quality Control

Our production of 4-(Chloromethyl)-1,3,2-Dioxathiolane 2-Oxide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its reactive nature, ensure containers are kept tightly sealed to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.