Description

(20S)-20-(Dimethylamino)-5α-Pregnane-3β,4α-Diol CAS NO 15112-49-9 is a high-purity, synthetic steroid derivative characterized by its specific stereochemistry at the 20-position. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for research and development. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of complex therapeutic agents and in analytical method development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for drug discovery programs.
• Biochemical Research: Investigated for its biological activity and potential interactions with steroid hormone receptors.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring high stereochemical purity.
• Analytical Standard: Serves as a certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	(20S)-20-(Dimethylamino)-5α-Pregnane-3β,4α-Diol
CAS No.	15112-49-9
Molecular Formula	C23H41NO2
Molecular Weight	363.58 g/mol
Synonyms	20-(Dimethylamino)-5α-pregnane-3β,4α-diol; (20S)-20-(Dimethylamino)pregnane-3β,4α-diol; 3β,4α-Dihydroxy-20-dimethylamino-5α-pregnane; 5α-Pregnane-3β,4α-diol, 20-(dimethylamino)-, (20S)-; NSC 113986
EINECS	Contact for details

Quality Control

Our (20S)-20-(Dimethylamino)-5α-Pregnane-3β,4α-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity (IR, NMR), and related substance profile is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.