Description

Hypophosphoric Acid Tetramethyl Ester is an organophosphorus compound, specifically the tetramethyl ester of hypophosphoric acid. This specialty chemical is valued for its role as a versatile intermediate and reagent in advanced synthetic chemistry. It is primarily sought after by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Ligand and Catalyst Precursor: Serves as a building block for creating specialized phosphonate-based ligands in coordination chemistry and catalysis.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and plant growth regulators.
• Flame Retardant Additive: Acts as a reactive intermediate in the manufacture of phosphorus-containing flame retardants for polymers and textiles.
• Material Science Research: Utilized in the development of metal-organic frameworks (MOFs), surface modifiers, and specialty polymers.
• Cross-Coupling Reactions: Functions as a reagent in palladium-catalyzed cross-coupling reactions for carbon-phosphorus bond formation.

Basic Information

Product Name	Hypophosphoric Acid Tetramethyl Ester
CAS No.	15103-99-8
Molecular Formula	C4H12O6P2
Molecular Weight	218.09 g/mol
Synonyms	Tetramethyl Hypophosphate; Dimethyl Phosphonate Dimer; Tetramethoxyphosphorane; P,P,P',P'-Tetramethyl Diphosphonate; Hypophosphoric Acid Methyl Ester; Tetramethyl Ester of Hypophosphoric Acid; Methyl Hypophosphate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to strict in-process controls to deliver material suitable for research and industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation. Keep away from heat, sparks, and open flame. Isolate from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.