Description

Hydrogen Tribromide, Compd. With 1-Methyl-2-Pyrrolidinone (1:2) is a stable, liquid complex of hydrogen bromide (HBr) with the polar aprotic solvent N-methyl-2-pyrrolidone (NMP). This formulation is crucial for providing a controlled, non-gaseous source of HBr, which is essential for precise bromination, ether cleavage, and acid-catalyzed reactions in sensitive synthetic processes. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries where handling safety and reagent consistency are paramount.

Application

• Pharmaceutical Intermediate Synthesis: As a source of HBr for regioselective bromination and demethylation reactions in active pharmaceutical ingredient (API) manufacturing.
• Polymer Chemistry: Catalyst and reagent for the modification of polymers and the synthesis of brominated flame retardants.
• Agrochemical Production: Used in the synthesis of bromine-containing herbicides, pesticides, and fungicides.
• Organic Synthesis: A versatile reagent for alkylation, cyclization, and as an acid catalyst in various condensation and esterification reactions.
• Laboratory Research: A convenient and safer alternative to gaseous HBr for small-scale exploratory synthesis and method development.
• Chemical Purification: Employed in purification processes where HBr is required for salt formation or decomposition of specific functional groups.

Basic Information

Product Name	Hydrogen Tribromide, Compd. With 1-Methyl-2-Pyrrolidinone (1:2)
CAS No.	14977-38-9
Molecular Formula	C10H20Br3N2O2
Molecular Weight	447.00 g/mol
Synonyms	Hydrogen Bromide - N-Methyl-2-pyrrolidone complex (2:1); HBr-NMP Complex; N-Methyl-2-pyrrolidinone hydrotribromide; Tribromide(1-), tris[μ-[1-methyl-2-pyrrolidinone-kO:kO']]dihydrogen; NMP-HBr Complex; 1-Methyl-2-pyrrolidinone hydrotribromide; Hydrogen bromide compd. with 1-methyl-2-pyrrolidinone (1:2)
EINECS	Contact for details

Quality Control

Our Hydrogen Tribromide-NMP complex is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HBr Content)	≥ 45.0 % w/w
Water Content (KF)	≤ 1.0 %
Related Substances (HPLC)	Contact for details
Specific Gravity (20°C)	~1.6 - 1.7

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.