Description

12-Chloro-12-Oxododecanoic Acid Ethyl Ester is a versatile bifunctional organic intermediate, combining both an acid chloride and an ester functional group within a long alkyl chain. This unique structure makes it a valuable building block for the synthesis of complex molecules, particularly in pharmaceutical and specialty chemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing carbon chains and introducing specific functional groups.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a dodecanoic acid backbone with terminal reactivity.
• Polymer Chemistry: Serves as a monomer or chain extender in the production of specialty polyesters and polyamides, contributing specific chain length and terminal functionality.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators where its long aliphatic chain is incorporated into the final molecule.
• Lubricant & Surfactant Additives: Intermediate for producing ester-based additives that modify viscosity, stability, and surface-active properties.
• Organic Synthesis Building Block: Employed in academic and industrial research for nucleophilic acyl substitution reactions, leveraging the reactive acid chloride group while the ethyl ester provides a protected carboxylic acid.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing macrocyclic musk compounds and other long-chain ester aroma chemicals.

Basic Information

Product Name	12-Chloro-12-Oxododecanoic Acid Ethyl Ester
CAS No.	14812-19-2
Molecular Formula	C14H25ClO3
Molecular Weight	276.80 g/mol
Synonyms	Ethyl 12-Chlorododecanoate; Ethyl 12-Chloro-12-oxododecanoate; Dodecanoyl chloride, ethyl ester; 12-Chlorododecanoic Acid Ethyl Ester; Ethyl ω-chlorododecanoate; 12-Chloro-12-oxo-dodecanoic acid ethyl ester; Ethyl 12-chloro-12-oxolaurate
EINECS	Contact for details

Quality Control

Our 12-Chloro-12-Oxododecanoic Acid Ethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable sourcing in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent derivative, it should be stored separately from bases, oxidizing agents, and moisture. Use appropriate corrosion-resistant storage materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.