Description

6-(Chloroformyl)Hexanoic Acid Ethyl Ester is a versatile bifunctional organic intermediate containing both an acid chloride and an ester functional group. This compound is critical for the synthesis of complex molecules, enabling the controlled introduction of a carboxylic acid derivative with a protected, extendable carbon chain. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing active pharmaceutical ingredients (APIs), novel crop protection agents, and functional monomers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating prodrugs or molecules with specific chain-length requirements.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require a functionalized hexanoic acid backbone.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for specialty polymers, coatings, and resins, imparting specific chemical functionality.
• Peptide Mimetics & Linker Chemistry: Employed in bioconjugation and the development of peptide analogs where the ethyl ester provides a handle for further modification or cleavage.
• Organic Synthesis Reagent: A valuable reagent in academic and industrial R&D for nucleophilic acyl substitution reactions, allowing sequential functionalization.
• Liquid Crystal & Electronic Chemical Production: Intermediate in the manufacture of advanced materials for display and electronic applications.

Basic Information

Product Name	6-(Chloroformyl)Hexanoic Acid Ethyl Ester
CAS No.	14794-32-2
Molecular Formula	C9H15ClO3
Molecular Weight	206.67 g/mol
Synonyms	Ethyl 6-Chloro-6-oxohexanoate; 6-Carboxyhexanoyl Chloride Ethyl Ester; Ethyl 6-Chloroformylhexanoate; Hexanoic Acid, 6-(Chloroformyl)-, Ethyl Ester; Adipic Acid Monochloride Ethyl Ester; 6-(Ethoxycarbonyl)hexanoyl Chloride; Adipoyl Chloride Monoethyl Ester
EINECS	Contact for details

Quality Control

Our 6-(Chloroformyl)Hexanoic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.