Description

Propanoic Acid, 2-Diazo-3-Oxo-, Ethyl Ester is a specialized diazo compound and a versatile reagent in organic synthesis. This product matters as a key building block for introducing the diazoacetyl functional group, enabling critical transformations in the synthesis of complex molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications such as cyclopropanation and carbene insertion reactions.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring cyclopropane rings or modified ester functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its reactive diazo group facilitates the construction of novel heterocyclic structures.
• Fine Chemical Manufacturing: Employed as a specialized reagent for the production of dyes, pigments, and performance chemicals requiring precise molecular architecture.
• Academic & Industrial Research: A valuable tool in method development and discovery chemistry for C-H functionalization and cross-coupling reactions catalyzed by transition metals.
• Polymer Chemistry: Can be utilized in the modification of polymers or as an initiator/chain transfer agent in controlled polymerization processes.

Basic Information

Product Name	Propanoic Acid, 2-Diazo-3-Oxo-, Ethyl Ester
CAS No.	14762-48-2
Molecular Formula	C5H6N2O3
Molecular Weight	142.11 g/mol
Synonyms	Ethyl 2-Diazo-3-oxopropanoate; Ethyl Diazoacetate, 3-Oxo-; Ethyl 2-Diazo-3-oxobutyrate (common misnomer); Diazoacetoacetic Ester; Ethyl Diazoacetoacetate; 2-Diazo-3-oxobutanoic Acid Ethyl Ester; Ethyl α-Diazoacetoacetate
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-Diazo-3-Oxo-, Ethyl Ester is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. This compound is light-sensitive and should be stored away from light. It is also easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, Ethyl Acetate)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.