Description

5-(Trifluoromethyl)Benzoxazol-2(3H)-One is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethylated benzoxazolone scaffold, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and organic electronic materials requiring fluorinated components.
• Chemical Biology Probes: Employed in the design of enzyme inhibitors and receptor ligands for biochemical pathway studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	5-(Trifluoromethyl)Benzoxazol-2(3H)-One
CAS No.	14733-68-7
Molecular Formula	C8H4F3NO2
Molecular Weight	203.12 g/mol
Synonyms	2-Benzoxazolinone, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-benzoxazolinone; 5-(Trifluoromethyl)-2(3H)-benzoxazolone; 5-Trifluoromethylbenzoxazol-2-one; 3H-Benzoxazol-2-one, 5-(trifluoromethyl)-; 14733-68-7; 5-Trifluoromethyl-2-benzoxazolinone
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Benzoxazol-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.