Description

3-(Chloromethyl)-5-Phenylisoxazole is a versatile heterocyclic building block featuring a reactive chloromethyl group attached to an isoxazole core. This compound is valued for its role as a key synthetic intermediate in the development of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, especially those containing the isoxazole pharmacophore known for various biological activities.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the isoxazole ring can contribute to bioactive properties.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Ligand and Catalyst Development: Utilized as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	3-(Chloromethyl)-5-Phenylisoxazole
CAS No.	14731-10-3
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	5-Phenyl-3-(chloromethyl)isoxazole; 3-Chloromethyl-5-phenylisoxazole; 5-Phenyl-3-chloromethylisoxazole; 3-(Chloromethyl)-5-phenyl-1,2-oxazole; (5-Phenylisoxazol-3-yl)methyl chloride; 14731-10-3; 5-Phenyl-3-isoxazolemethyl chloride
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-5-Phenylisoxazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets the agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.