Description

3-(4-Chlorophenylsulfonyl)Propionic Acid Ethyl Ester is a high-purity organic sulfone ester building block of significant importance in advanced chemical synthesis. This compound serves as a versatile intermediate for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the chlorophenylsulfonyl moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions and nucleophilic substitution reactions to introduce functionalized propionate groups.
• Ligand Precursor: Can be modified to create novel sulfonyl-based ligands for catalytic applications in asymmetric synthesis.
• Chemical Biology Probe Development: Used to create activity-based probes for studying enzyme function and mechanism.

Basic Information

Product Name	3-(4-Chlorophenylsulfonyl)Propionic Acid Ethyl Ester
CAS No.	14725-83-8
Molecular Formula	C11H13ClO4S
Molecular Weight	276.74 g/mol
Synonyms	Ethyl 3-((4-chlorophenyl)sulfonyl)propanoate; Ethyl 4-Chlorobenzenesulfonylpropionate; 3-(p-Chlorophenylsulfonyl)propionic Acid Ethyl Ester; 4-Chlorobenzenesulfonylpropionic Acid Ethyl Ester; NSC 163063; Benzenesulfonic acid, 4-chloro-, 3-ethoxy-3-oxopropyl ester; Propanoic acid, 3-[(4-chlorophenyl)sulfonyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenylsulfonyl)Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.