Description

n-Diazoacetyl-L-Phenylalanine Hydrazide is a specialized diazo compound that serves as a versatile biochemical building block. Its unique structure, featuring both a diazoacetyl group and a hydrazide moiety, makes it a valuable precursor for synthesizing enzyme inhibitors and affinity labeling agents. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and life science sectors for developing targeted therapeutic agents and conducting proteomic studies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of protease inhibitors and other targeted small-molecule drugs.
• Biochemical Research: Used as an active-site directed irreversible inhibitor for studying enzyme mechanisms, particularly serine proteases.
• Affinity Labeling Probe: Employed to tag and isolate specific enzymes or receptors in complex biological mixtures for proteomics.
• Peptide & Protein Modification: Facilitates the site-specific introduction of reactive groups into peptides and proteins for conjugation or functional studies.
• Chemical Biology Tool: Enables the exploration of biological pathways and the validation of drug targets through covalent modification.

Basic Information

Product Name	n-Diazoacetyl-L-Phenylalanine Hydrazide
CAS No.	14722-72-6
Molecular Formula	C11H12N4O3
Molecular Weight	248.24 g/mol
Synonyms	Diazoacetylphenylalanine Hydrazide; L-Phenylalanine, N-[2-(diazoacetyl)]-, hydrazide; N-Diazoacetyl-L-phenylalanine hydrazide; Azaserine Precursor; Enzyme Inhibitor Precursor; Affinity Labeling Agent; DAPH
EINECS	Contact for details

Quality Control

Our n-Diazoacetyl-L-Phenylalanine Hydrazide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for the handling of advanced pharmaceutical intermediates to support our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.