Description

Diacetone-D-Glucose is a protected sugar derivative, specifically the 1,2:5,6-di-O-isopropylidene derivative of D-glucose. This compound is a crucial chiral intermediate and building block in organic synthesis, valued for its ability to mask reactive hydroxyl groups and provide stereochemical control. It is primarily needed by manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the production of nucleosides, antiviral agents, and other complex bioactive molecules.

Application

• Pharmaceutical Synthesis: A key chiral starting material for the production of nucleoside analogs and antiviral drugs.
• Agrochemical Intermediates: Used in the synthesis of advanced, stereospecific pesticides and herbicides.
• Fine Chemical Production: Serves as a versatile building block for complex carbohydrates, flavors, and fragrances.
• Glycochemistry Research: An essential reagent for the study and synthesis of oligosaccharides and glycoconjugates.
• Polymer Chemistry: Acts as a monomer or initiator for creating specialized, biodegradable polymers.
• Chemical Derivatization: Used to protect sugar moieties during multi-step synthetic sequences.

Basic Information

Product Name	Diacetone-D-Glucose
CAS No.	14686-89-6
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose; 1,2:5,6-Di-O-isopropylidene-D-glucofuranose; Diacetone glucose; Di-O-isopropylidene-D-glucose; DAG; 1,2:5,6-Diisopropylidene-D-glucofuranose; α-D-Glucofuranose, 1,2:5,6-di-O-(1-methylethylidene)-
EINECS	238-727-8

Quality Control

Our Diacetone-D-Glucose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use as a pharmaceutical intermediate. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-18° to -20° (c=1 in H2O)
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.