Description

1-(2-Chlorophenyl)-1H-Pyrazol-5-Amine CAS NO 14678-96-7 is a versatile heterocyclic aromatic amine building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a reactive amine group and a halogenated pyrazole ring, enabling its use in constructing complex molecular architectures. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, and specialty polymers due to its electron-donating amine and rigid aromatic structure.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Dye & Pigment Intermediate: Functions as a starting material for synthesizing specialized azo dyes and colorants with specific light-fastness and chromatic properties.
• Academic & Contract Research: A valuable reagent for methodological studies in heterocyclic chemistry, cross-coupling reactions, and amine functionalization.

Basic Information

Product Name	1-(2-Chlorophenyl)-1H-Pyrazol-5-Amine
CAS No.	14678-96-7
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	5-Amino-1-(2-chlorophenyl)-1H-pyrazole; 1-(2-Chlorophenyl)-1H-pyrazol-5-amine; 2-Chlorophenyl-5-aminopyrazole; 5-Amino-1-(2-chlorophenyl)pyrazole; 1H-Pyrazol-5-amine, 1-(2-chlorophenyl)-; 1-(o-Chlorophenyl)-1H-pyrazol-5-amine; 1-(2-Chlorophenyl)-5-aminopyrazole; 2-Chloro-5-aminophenylpyrazole
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)-1H-Pyrazol-5-Amine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthesis applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.