Description

p-Fluorobenzyloxytrimethylsilane is a versatile organosilicon reagent featuring a fluorinated benzyl protecting group. This compound is valued for its role as a key synthetic intermediate and protecting agent in advanced organic synthesis, particularly for sensitive functional groups. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Protecting Group Reagent: Used to protect hydroxyl groups during multi-step synthetic sequences, offering stability under various reaction conditions.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides where the p-fluorobenzyl moiety is required.
• Material Science Precursor: Employed in the synthesis of functionalized silanes for surface modification, coatings, and advanced polymer materials.
• Cross-Coupling Reactions: Acts as a substrate or reagent in palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Liquid Crystal & OLED Material Research: Used in the development of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.

Basic Information

Product Name	p-Fluorobenzyloxytrimethylsilane
CAS No.	14629-55-1
Molecular Formula	C10H15FOSi
Molecular Weight	198.31 g/mol
Synonyms	Trimethyl[(4-fluorophenyl)methoxy]silane; (4-Fluorobenzyloxy)trimethylsilane; 1-[(Trimethylsilyl)oxy]methyl-4-fluorobenzene; p-Fluorobenzyl O-Trimethylsilyl Ether; 4-Fluorobenzyloxytrimethylsilane; O-[(4-Fluorophenyl)methyl]trimethylsilanol; TMS-O-CH2-C6H4-F-4
EINECS	Contact for details

Quality Control

Our p-Fluorobenzyloxytrimethylsilane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for critical applications to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.