Description

5-Aminothiophene-2-Carboxylicmethylesterhydrochloride is a versatile and high-value heterocyclic building block, primarily used in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a reactive amino group and an ester moiety, which makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides due to the bioactivity of the thiophene scaffold.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and advanced dyes or pigments.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry, coupling reactions, and as a ligand precursor in catalysis.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	5-Aminothiophene-2-Carboxylicmethylesterhydrochloride
CAS No.	14597-57-0
Molecular Formula	C7H10ClNO2S
Molecular Weight	207.68 g/mol
Synonyms	Methyl 5-aminothiophene-2-carboxylate hydrochloride; 2-Thiophenecarboxylic acid, 5-amino-, methyl ester, hydrochloride; 5-Amino-2-thiophenecarboxylic acid methyl ester hydrochloride; Methyl 5-amino-2-thiophenecarboxylate hydrochloride; 5-Amino-2-methoxycarbonylthiophene hydrochloride; 5-Amino-2-(methoxycarbonyl)thiophene hydrochloride; 5-Aminothiophene-2-methyl carboxylate HCl
EINECS	Contact for details

Quality Control

Our 5-Aminothiophene-2-Carboxylicmethylesterhydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.