Description

Ethyl 5-Bromo-4-oxopentanoate is a versatile brominated ketoester intermediate of significant importance in advanced organic synthesis. This compound is valued for its bifunctional reactivity, featuring both an electrophilic bromoalkyl group and a nucleophilic carbonyl/ester moiety, enabling its use in complex molecular construction. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing heterocyclic compounds, active pharmaceutical ingredients (APIs), and potential drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific brominated structures.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & R&D: Essential reagent in medicinal chemistry research for structure-activity relationship (SAR) studies and novel compound library generation.
• Peptide Mimetics: Utilized in the synthesis of peptidomimetics and constrained amino acid analogs.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.

Basic Information

Product Name	Ethyl 5-Bromo-4-oxopentanoate
CAS No.	14594-25-3
Molecular Formula	C7H11BrO3
Molecular Weight	223.07 g/mol
Synonyms	5-Bromo-4-oxopentanoic acid ethyl ester; Ethyl 5-bromo-4-oxovalerate; 4-Oxopentanoic acid, 5-bromo-, ethyl ester; 5-Bromo-4-oxovaleric acid ethyl ester; Ethyl 5-bromolevulinate; 5-Bromolevulinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-4-oxopentanoate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and organic solvent compatibility, ensure containers are kept sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.