Description

2,3-Dihydro-1H-Indene-1,2-Diamine is a versatile chiral diamine building block featuring a fused indane core structure. This compound is valued for its rigid, bicyclic framework which is instrumental in the synthesis of complex molecules with defined stereochemistry. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly in the development of active pharmaceutical ingredients (APIs) and advanced ligands for catalysis.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, including central nervous system (CNS) agents and enzyme inhibitors.
• Asymmetric Catalyst Ligand: Used to construct sophisticated chiral ligands for transition metal catalysis, enabling enantioselective synthesis.
• Fine Chemical Synthesis: Serves as a building block for complex organic molecules, agrochemicals, and specialty polymers.
• Research & Development: Essential reagent in academic and industrial R&D for exploring new chemical entities and synthetic methodologies.
• Resolution Agent: Potential use in the chiral resolution of racemic mixtures due to its inherent chirality.

Basic Information

Product Name	2,3-Dihydro-1H-Indene-1,2-Diamine
CAS No.	14563-24-7
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(1R,2R)-1,2-Diaminoindane; (1S,2S)-1,2-Diaminoindane; 1,2-Diaminoindane; rac-1,2-Diaminoindane; Indane-1,2-diamine; 1,2-Indanediamine; trans-1,2-Diaminoindane; DACH-n (derivative)
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Indene-1,2-Diamine is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider using an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee (for enantiopure grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.