Description

2-Amino-3-Chlorobutyric Acid is a halogenated, non-proteinogenic amino acid derivative that serves as a versatile chiral building block in advanced organic synthesis. Its unique structure, featuring both an amino and a chloro functional group on adjacent carbon atoms, makes it a critical intermediate for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and plant growth regulators.
• Peptide Research & Modification: Employed to introduce chlorinated amino acid residues into peptide chains, altering their stability, bioavailability, and receptor binding properties.
• Chemical Biology Probes: Serves as a building block for creating labeled or modified amino acids used to study enzyme mechanisms and protein interactions.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Fine Chemical Production: A precursor for various specialty chemicals, including liquid crystals, complex ligands, and advanced polymer additives.

Basic Information

Product Name	2-Amino-3-Chlorobutyric Acid
CAS No.	14561-56-9
Molecular Formula	C₄H₈ClNO₂
Molecular Weight	137.56 g/mol
Synonyms	3-Chloro-2-aminobutyric Acid; (±)-2-Amino-3-chlorobutanoic Acid; DL-2-Amino-3-chlorobutyric Acid; 3-Chloro-DL-2-aminobutyric Acid; 2-Amino-3-chloro-butanoic acid; α-Amino-β-chlorobutyric Acid; ACBA; 14561-56-9
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chlorobutyric Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.