Description

1,1,1-Trifluoro-3-(2-Thienyl)Acetone is a high-value fluorinated organic building block characterized by its unique trifluoromethyl and thiophene functionalities. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure imparts desirable metabolic stability and lipophilicity. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for improved performance.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostics.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	1,1,1-Trifluoro-3-(2-Thienyl)Acetone
CAS No.	14529-33-0
Molecular Formula	C7H5F3OS
Molecular Weight	194.17 g/mol
Synonyms	3-(2-Thienyl)-1,1,1-trifluoroacetone; 1,1,1-Trifluoro-3-(thiophen-2-yl)propan-2-one; 2-Thienyltrifluoroacetone; 2-Thienyl trifluoromethyl ketone; 3-(2-Thienyl)-1,1,1-trifluoro-2-propanone; 2-Propanone, 1,1,1-trifluoro-3-(2-thienyl)-; TFTA; α,α,α-Trifluoro-2-thienylacetone
EINECS	Contact for details

Quality Control

Every batch of 1,1,1-Trifluoro-3-(2-Thienyl)Acetone is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.