Description

1-Bromo-4-Chloro-2-Methylbenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its ability to undergo selective cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, serving as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific halogen-substituted aromatic cores.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the bromo and chloro substituents allow for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where halogenated benzene derivatives are key structural units.
• Chemical Research & Development: A valuable reagent for exploring new organic reactions and methodologies in academic and industrial R&D laboratories.
• Dye and Pigment Intermediate: Acts as a building block in the production of complex dyes and organic pigments.

Basic Information

Product Name	1-Bromo-4-Chloro-2-Methylbenzene
CAS No.	14495-51-3
Molecular Formula	C7H6BrCl
Molecular Weight	205.48 g/mol
Synonyms	4-Chloro-1-bromo-2-methylbenzene; 2-Bromo-5-chlorotoluene; 5-Chloro-2-bromotoluene; 1-Bromo-4-chloro-o-xylene; 2-Methyl-4-chlorobromobenzene; 4-Chloro-2-methylbromobenzene; Toluene, 2-bromo-5-chloro-; Bromochlorotoluene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Chloro-2-Methylbenzene is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.