Description

Tetramethyl-1,2,3,4-Cyclobutanetetracarboxylate is a high-purity, multifunctional organic building block and key synthetic intermediate. This compound is valued for its rigid, symmetrical cyclobutane core and four ester functionalities, which enable its use in advanced material synthesis and pharmaceutical chemistry. It is primarily sought by R&D chemists and process engineers in the fine chemical, pharmaceutical, and polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), leveraging its stereochemistry and functional handles.
• Ligand and Catalyst Synthesis: Used to construct sophisticated, multi-dentate ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Acts as a cross-linking agent or monomer for producing high-performance polymers, resins, and specialty materials with enhanced thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, [2+2] cycloadditions, and other cyclization strategies to create novel polycyclic compounds.
• Agrochemical Research: Utilized in the development of new crop protection agents and herbicides due to its structural complexity.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in research laboratories.

Basic Information

Product Name	Tetramethyl-1,2,3,4-Cyclobutanetetracarboxylate
CAS No.	14495-41-1
Molecular Formula	C12H16O8
Molecular Weight	288.25 g/mol
Synonyms	1,2,3,4-Cyclobutanetetracarboxylic acid, tetramethyl ester; Tetramethyl cyclobutane-1,2,3,4-tetracarboxylate; Cyclobutane-1,2,3,4-tetracarboxylic acid tetramethyl ester; TMCT; Tetramethyl cyclobutanetetracarboxylate; Dimethyl cyclobutanetetracarboxylate (common misnomer)
EINECS	Contact for details

Quality Control

Our Tetramethyl-1,2,3,4-Cyclobutanetetracarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.