Description

Methyl (2E)-2-Cyano-3-(4-Methoxyphenyl)Prop-2-Enoate, also known as Methyl trans-α-Cyano-4-Methoxycinnamate or 4-[(1E)-2-Cyano-3-Methoxy-3-Oxoprop-1-En-1-Yl]Anisole, is a high-value, versatile cinnamate derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring a conjugated cyanoacrylate moiety and a methoxyphenyl group, makes it an essential intermediate for creating compounds with specific electronic and photophysical properties. This compound is particularly sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides, leveraging its reactive functional groups.
• Organic Electronic Materials: Serves as a precursor in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and non-linear optical (NLO) materials due to its electron-accepting and π-conjugated system.
• UV Absorber & Sunscreen Agent Precursor: Functions as a core structure in the manufacturing of advanced organic UV filters for personal care and polymer stabilization applications.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the methoxy and cyano groups influence color and stability.
• Cross-Coupling Reactions: Acts as a competent substrate in various palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) for constructing complex biaryl systems.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and material science research.

Basic Information

Product Name	Methyl (2E)-2-Cyano-3-(4-Methoxyphenyl)Prop-2-Enoate
CAS No.	14479-58-4
Molecular Formula	C12H11NO3
Molecular Weight	217.22 g/mol
Synonyms	Methyl trans-α-Cyano-4-Methoxycinnamate; 4-[(1E)-2-Cyano-3-Methoxy-3-Oxoprop-1-En-1-Yl]Anisole; Methyl 2-Cyano-3-(4-methoxyphenyl)acrylate; (2E)-2-Cyano-3-(4-methoxyphenyl)-2-propenoic Acid Methyl Ester; trans-2-Cyano-3-(4-methoxyphenyl)acrylic Acid Methyl Ester; Methyl (E)-2-Cyano-3-(4-methoxyphenyl)acrylate; p-Methoxy-α-cyanocinnamic Acid Methyl Ester; Methyl 4-Methoxy-α-cyanocinnamate
EINECS	Contact for details

Quality Control

Our Methyl (2E)-2-Cyano-3-(4-Methoxyphenyl)Prop-2-Enoate is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Production adheres to current industry best practices, and each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key specifications such as identity, purity, and impurity profile. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.