Description

2,2,2-Trifluoroacetate is a versatile chemical intermediate and reagent characterized by its trifluoromethyl group. This compound matters for its role in introducing fluorine atoms into target molecules, a key strategy in modern pharmaceutical and agrochemical development to enhance metabolic stability and bioavailability. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesis and derivatization processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the trifluoromethyl group improves efficacy.
• Peptide Synthesis & Protection: Serves as a protecting group for amines or as an activating agent in peptide coupling reactions.
• Organic Synthesis Reagent: Employed as a trifluoroacetylating agent in various organic transformations and material science applications.
• Analytical Chemistry: Utilized as a derivatization agent in gas chromatography and mass spectrometry for analyte detection.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material for synthesizing fluorinated components in electronic displays.

Basic Information

Product Name	2,2,2-Trifluoroacetate
CAS No.	14477-72-6
Molecular Formula	C2HF3O2
Molecular Weight	114.03 g/mol
Synonyms	Trifluoroacetic Acid, Sodium Salt; Sodium Trifluoroacetate; Trifluoroacetate Ion; TFA Salt; CF3COONa; 2,2,2-Trifluoroacetic Acid Sodium Salt; Sodium 2,2,2-Trifluoroacetate
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroacetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the required specifications for purity and consistency. Certificates of Analysis (COA) documenting key parameters such as assay, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent derivative, keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.