Description

(R)-(-)-2-tert-Butylamino-1-Phenylethanol is a chiral amino alcohol compound of significant importance in asymmetric synthesis and pharmaceutical chemistry. Its value lies in its role as a versatile chiral building block and resolving agent for the production of enantiomerically pure substances. This high-purity intermediate is essential for research and manufacturing in the pharmaceutical industry, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly β-adrenergic blockers and other cardiovascular agents.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce high enantioselectivity.
• Chiral Resolution Agent: Used to separate racemic mixtures of acids or other compounds via diastereomeric salt formation.
• Fine Chemical Production: Serves as a precursor in the manufacture of complex, high-value specialty chemicals and agrochemicals.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chiral transformations in research laboratories.

Basic Information

Product Name	(R)-(-)-2-tert-Butylamino-1-Phenylethanol
CAS No.	14467-51-7
Molecular Formula	C₁₂H₁₉NO
Molecular Weight	193.29 g/mol
Synonyms	(R)-(-)-2-(tert-Butylamino)-1-phenylethanol; (R)-2-(tert-Butylamino)-1-phenylethanol; (R)-N-tert-Butyl-2-amino-1-phenylethanol; (R)-(-)-N-tert-Butylnorephedrine; (R)-(-)-tert-Butylnorephedrine; (1R)-2-[(1,1-Dimethylethyl)amino]-1-phenylethanol; (R)-Phenylephrine tert-butylamine derivative
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-tert-Butylamino-1-Phenylethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air and light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.