Description

3'-Iodoacetophenone is a versatile aromatic ketone building block characterized by its iodine substituent at the meta position. This compound is highly valued in organic synthesis for its reactivity, particularly in cross-coupling reactions and as a precursor for more complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for the development of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring aryl-iodide motifs for further functionalization.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where the iodoacetophenone structure serves as a core building block.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive materials due to its electron-accepting carbonyl group and halogen atom.
• Cross-Coupling Reactions: Serves as a crucial substrate in palladium-catalyzed reactions such as Suzuki, Heck, and Sonogashira couplings to form new carbon-carbon bonds.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Ligand and Catalyst Preparation: Utilized as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	3'-Iodoacetophenone
CAS No.	14452-30-3
Molecular Formula	C8H7IO
Molecular Weight	246.05 g/mol
Synonyms	1-(3-Iodophenyl)ethanone; 3-Iodoacetophenone; m-Iodoacetophenone; 3-Acetyliodobenzene; 3-Iodophenyl methyl ketone; 1-Acetyl-3-iodobenzene; Ethanone, 1-(3-iodophenyl)-
EINECS	Contact for details

Quality Control

Our 3'-Iodoacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.