Description

(R)-1-Bromo-2,3-Dihydroxypropane is a chiral building block of significant importance in asymmetric synthesis, valued for its reactive bromine and hydroxyl functionalities. This compound is essential for the production of high-value intermediates in the pharmaceutical and fine chemical industries, where stereochemical purity is critical. It is primarily needed by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers, antiviral agents, and other optically active drugs.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complexes.
• Polymer Modification: Employed to introduce functional groups into polymer chains for specialty materials with tailored properties.
• Bioconjugation Chemistry: Useful for linking biomolecules due to its reactive halogen and hydroxyl groups.
• Academic and R&D: A valuable reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	(R)-1-Bromo-2,3-Dihydroxypropane
CAS No.	14437-88-8
Molecular Formula	C3H7BrO2
Molecular Weight	154.99 g/mol
Synonyms	(R)-3-Bromo-1,2-propanediol; (R)-3-Bromopropane-1,2-diol; (R)-1-Bromo-2,3-dihydroxypropane; (R)-3-Bromopropylene glycol; (R)-β-Bromohydrin glycerol; (R)-Glycidyl bromide hydrobromide (related); (R)-1-Bromo-2,3-propanediol
EINECS	Contact for details

Quality Control

Our (R)-1-Bromo-2,3-Dihydroxypropane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.