Description

N2,N6-Bis(1-Oxododecyl)-L-Lysine is a synthetic, lipophilic derivative of the essential amino acid L-lysine, where two lauroyl (dodecanoyl) groups are attached to the alpha and epsilon amino groups. This chemical modification is critical for enhancing the molecule's amphiphilic character and membrane permeability, making it a valuable intermediate in advanced material and life science research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, cosmetic, and specialty chemical sectors for developing novel drug delivery systems, bio-conjugates, and functional surfactants.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs and peptide conjugates to improve lipophilicity and bioavailability of active pharmaceutical ingredients (APIs).
• Lipid-Based Drug Delivery: Serves as a key building block for constructing lipid nanoparticles (LNPs), liposomes, and other nano-carriers for targeted drug and gene delivery.
• Cosmetic & Personal Care Actives: Employed in the formulation of advanced skincare products as a carrier for active ingredients, enhancing skin penetration and stability.
• Bioconjugation & Protein Labeling: Acts as a linker or spacer arm for attaching hydrophobic tags, fluorophores, or drugs to proteins, antibodies, or peptides.
• Surfactant & Emulsifier Research: Studied for its unique surfactant properties in creating stable emulsions and micelles for industrial and laboratory applications.
• Biomaterials & Polymer Science: Incorporated into polymers and hydrogels to modify surface properties, degradation rates, and cell-material interactions.

Basic Information

Product Name	N2,N6-Bis(1-Oxododecyl)-L-Lysine
CAS No.	14379-54-5
Molecular Formula	C30H56N2O5
Molecular Weight	524.78 g/mol
Synonyms	Nα,Nε-Dilauroyl-L-lysine; N2,N6-Didodecanoyl-L-lysine; L-Lysine, N2,N6-bis(1-oxododecyl)-; Dilauroyl-L-lysine; Nα,Nε-Bis(dodecanoyl)-L-lysine; Lys(Dodecanoyl)2; N,N-Bis(lauroyl)-L-lysine
EINECS	Contact for details

Quality Control

Our N2,N6-Bis(1-Oxododecyl)-L-Lysine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.