Description

1-Phenylcyclobutanecarbonitrile is a versatile organic nitrile building block characterized by its unique phenyl-substituted cyclobutane ring structure. This compound is valued for its role as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular frameworks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging its rigid cyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in polymer chemistry to introduce cyclobutane units, modifying thermal and mechanical properties.
• Organic Synthesis Building Block: Utilized in cycloaddition reactions and ring-opening transformations to access diverse chemical space in medicinal chemistry.
• Fine Chemical Production: Acts as an intermediate for dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	1-Phenylcyclobutanecarbonitrile
CAS No.	14377-68-5
Molecular Formula	C11H11N
Molecular Weight	157.21 g/mol
Synonyms	1-Phenylcyclobutanecarbonitrile; 1-Phenylcyclobutanenitrile; 1-Cyano-1-phenylcyclobutane; Cyclobutylphenylacetonitrile; (1-Phenylcyclobutyl)carbonitrile; 1-Phenyl-1-cyanocyclobutane; α-Phenylcyclobutanecarbonitrile; Phenylcyclobutanenitrile
EINECS	Contact for details

Quality Control

Our 1-Phenylcyclobutanecarbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.